What is Dr. Grandel Beautyness Professional+ Niacinamid Serum?
Dr. Grandel Beautyness Professional+ Niacinamid Serum is a refining, smoothing active-ingredient concentrate. Dr. Grandel formulated it for professional device-assisted facials, as a multifunctional niacinamide serum for tone, texture and sebum control. It is also one of the eight PROFESSIONAL+ formulas in Dr. Grandel’s Beautyness system. The brand built this facial-treatment line to work alongside device-based modalities, such as ultrasound and cosmetic microneedling.
Dr. Grandel positions the PROFESSIONAL+ series for "intensive results in cosmetic treatments, in combination with beauty technologies." In addition, the brand formulated the series for compatibility with ultrasound at 3 MHz and above. It also formulated the series for compatibility with cosmetic microneedling up to 0.5 mm. For professional use by licensed estheticians only.
Key benefits
- Multifunctional niacinamide serum: formulated to improve the look of skin tone and also reduce the appearance of visible lines.
- Barrier support: positioned to strengthen the look of barrier lipids.
- Sebum regulation: formulated to help regulate the appearance of excess oil.
- Built for device-assisted treatments: ideal for use with ultrasound and superficial microneedling (up to 0.5 mm) protocols.
Key ingredients
Dr. Grandel builds this serum around niacinamide, a multifunctional active. Specifically, the brand positions it to support the look of even skin tone and reduce the appearance of visible lines. Dr. Grandel also positions it to strengthen the skin’s barrier lipids and help regulate the look of excess sebum. Overall, the brand formulated it for compatibility with device-assisted treatments.
However, Dr. Grandel has not published a full brand-direct ingredient (INCI) list for this product on grandel.com. Instead, the description reflects the brand’s official Beautyness PROFESSIONAL+ materials and its authorized US distributor listings.
How to use Beautyness Niacinamid Serum
- For use by a licensed esthetician as part of a professional facial protocol.
- Then dispense as directed for the chosen modality (ultrasound or superficial microneedling).
- Apply to clean, prepped skin immediately before or during the device treatment, per your facility’s protocol.
- Finally, follow with the appropriate Beautyness PROFESSIONAL+ post-treatment products, such as Calm Mask or Pure Cream.
For professional use only. Not intended for unsupervised home use. Avoid the eye area; discontinue if irritation occurs.
Who Beautyness Niacinamid Serum is for
This serum is intended for licensed estheticians and medical spa practitioners who run ultrasound or superficial microneedling protocols. Specifically, its place is the treatment step, for clients dealing with uneven tone, visible lines or excess oil.
Retail size vs. professional size
This is a professional-only formula, distinct from the retail Timeless Niacinamid Serum that Dr. Grandel sells on grandel.com. In addition, Dr. Grandel does not sell this Beautyness version as a retail product. Instead, this listing is the standard 50 ml professional dispenser bottle.
Full ingredient list (INCI)
No brand-direct INCI list was published for this Beautyness product on grandel.com at the time of writing. Check the ingredient panel on the bottle you receive for the complete list.




