Dr. Grandel Epigen Advanced+: what is it?
Dr. Grandel Epigen Advanced+ is the ampoule for the weeks between salon visits. It fits the times when you still want a treatment-grade step at home.
This 3 x 3 ml box is part of Dr. Grandel’s Ampoule Excellence line, its most concentrated at-home tier. At its core is an epigenetic approach to skin aging. That approach aims to support the skin’s own regenerative processes rather than work on the surface alone. Each sealed, single-dose glass ampoule also absorbs quickly, leaving skin feeling silky and well-nourished.
Key benefits of Dr. Grandel Epigen Advanced+
- Smoother, firmer-looking skin: formulated to reduce the appearance of lines, wrinkles and expression lines with regular use.
- Support against the look of photoaging: sunflower sprout extract is included to help counter the visible effects of sun exposure as well as reduce the look of pigment spots.
- A more rejuvenated-looking tone: Retin Royal, a well-tolerated retinoid ester formulated to even out skin texture.
- Comfortable, non-greasy feel: squalane closely mirrors the skin’s own lipids for a nourishing rather than heavy finish.
Key ingredients
Hydroxypinacolone Retinoate, which Dr. Grandel calls Retin Royal, is an ester form of retinoic acid. The brand formulates it to be gentler than classic retinol, while still supporting visible cell renewal and a smoother-looking texture.
In addition, sunflower sprout extract targets the visible signs of photoaging and pigment spots. Finally, squalane rounds out the formula with a comfortable, skin-like finish. The concentrate also contains fragrance.
How to use Dr. Grandel Epigen Advanced+
- Cleanse your skin thoroughly.
- Wrap the ampoule in a tissue before you snap it open at the marked point.
- Then smooth the full dose over face, neck and décolleté.
- Afterward, follow with your usual moisturizer.
- Use two to three times a week for a course. Treat it as the at-home counterpart to an in-salon Epigen Advanced+ treatment.
Use the entire ampoule after you open it. Because it contains a retinoid ester, apply it in the evening and follow with daytime sun protection. For external use only, avoiding the eye area, and keep out of children’s reach.
Who it is for
This box is for anyone who wants a salon-grade anti-aging ampoule rather than an everyday hydrating step. Specifically, it is for use at home between professional treatments. Dr. Grandel positions Epigen Advanced+ as the top tier of its at-home ampoule range.
Retail size vs. professional size
This is the 3 x 3 ml retail box, sized for at-home use between salon visits. Dr. Grandel also offers Epigen Advanced+ in a professional size for estheticians who build it into in-treatment protocols.
Full ingredient list (INCI)
Aqua (Water), Neopentyl Glycol Diheptanoate, C12-15 Alkyl Benzoate, Diisopropyl Adipate, Glycerin, Pentylene Glycol, Propylheptyl Caprylate, Maltodextrin, Squalane, Polyglyceryl-6 Laurate, Lauryl Glucoside, Myristyl Glucoside, Acacia Senegal Gum, Xanthan Gum, Sodium Stearoyl Glutamate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Tocopherol, Caprylhydroxamic Acid, Helianthus Annuus (Sunflower) Sprout Extract, Acetyl Hexapeptide-1, Tetramethyl Acetyloctahydronaphthalenes, Limonene, Citrus Limon (Lemon) Peel Oil, Linalool, Linalyl Acetate, Alpha-Isomethyl Ionone, Hydroxycitronellal, Benzyl Salicylate, Juniperus Virginiana Oil, Pinene, Citrus Aurantium Peel Oil, Hexyl Cinnamal, Geraniol, Parfum (Fragrance)
Ingredient list per Dr. Grandel (grandel.com). Formulas can change; always check the list on the package you receive.
