What are Dr. Grandel Retinol Ampoules in professional size?
Dr. Grandel Retinol Ampoules in the professional size come as a box of 12 glass ampoules. Each ampoule holds 3 ml of a night-time active-ingredient concentrate built around retinol. Individual sealing keeps the retinol stable and fresh until you break the ampoule open.
Estheticians use this larger box to build multi-week retinol programs for clients. They also keep it on hand for back-bar treatments. Meanwhile, home users appreciate the lower per-ampoule cost compared to the 3-count retail box.
Key benefits
- Visible overnight smoothing: retinol is formulated to reduce the look of lines and wrinkles overnight, including more pronounced ones.
- Full treatment coverage: 12 ampoules support a 4 to 6 week program at two to three uses a week. As a result, you do not run out partway through.
- Consistent freshness: because each dose has its own seal, later ampoules in the box perform the same as the first.
- Lower cost per use: buying the 12-count box reduces the price per ampoule compared to the 3-count retail size.
Key ingredients
Retinol, a vitamin A derivative, is the ampoule’s core active. Skincare formulas use it to support a visibly smoother, more refined skin surface with regular use.
Tocopherol (vitamin E) adds antioxidant support. In addition, glycerin and PEG-40 hydrogenated castor oil help the light concentrate spread evenly and absorb comfortably. The single-ampoule format also protects the light-sensitive retinol until the moment of use. Note that the formula contains fragrance.
How to use Dr. Grandel Retinol Ampoules in professional size
- In the evening, cleanse and tone the skin as usual before use.
- Tap the ampoule so no liquid remains in the head. Then wrap it in a tissue and break it away from you at the marked dot.
- Pour the contents into your palm and press the concentrate onto the face, neck and décolleté. Then massage in gently.
- Use it as your night care, or follow with a Dr. Grandel night cream if you prefer.
- Finally, for a full course, use one ampoule two to three times a week for 4 to 6 weeks. This 12-count box comfortably covers that.
Use the contents of an ampoule immediately after opening. Do not save an opened ampoule for later.
Because the formula contains vitamin A (retinol), consider your total daily vitamin A intake before use. Also avoid the eye area. Do not open the ampoule with bare hands or pat it directly onto the skin. For external use only. Keep out of reach of children.
Who it is for
This 12-ampoule box suits anyone planning a longer retinol course. It is also a practical back-bar choice for estheticians who use the Retinol Ampoule in professional facials. Dr. Grandel recommends it for normal, dry, combination and oily skin.
Retinol is more active than an everyday moisturizer. For this reason, ease in with two applications a week. Also wear a broad-spectrum sunscreen by day while using it.
Dr. Grandel Retinol Ampoules: retail size vs. professional size
This listing is the 12 x 3 ml professional size. It works out to a lower cost per ampoule than the 3 x 3 ml retail box. It is also the size most estheticians choose for back-bar stock or for clients committing to a full course.
However, shoppers who want to try the formula first may prefer the 3-ampoule retail box. The same goes for anyone who only needs a short course.
Full ingredient list (INCI)
Aqua (Water), Glycerin, Pentylene Glycol, PEG-40 Hydrogenated Castor Oil, Trideceth-9, Lecithin, Xanthan Gum, Alcohol, Polysorbate 20, Retinol, Propylene Glycol, Benzotriazolyl Dodecyl p-Cresol, Disodium EDTA, Potassium Phosphate, Sodium Hydroxide, Tris (Tetramethylhydroxypiperidinol) Citrate, Tocopherol, Hexanoyl Dipeptide-3 Norleucine Acetate, Phenoxyethanol, Linalyl Acetate, Trimethylbenzenepropanol, Geranyl Acetate, Parfum (Fragrance), CI 19140 (Yellow 5), CI 42090 (Blue 1)
Ingredient list per Dr. Grandel (grandel.com), confirmed on the 3 ml Retinol Ampoule product page; the 12-count professional box uses the same formula. Formulas can change; always check the list on the package you receive.






