The Sensiderm Stress Protect Cream is formulated as an SOS day-and-night moisturizer for dry, reactive, and redness-prone skin. Its hero functional complex is Defensil® — a blend of Echium plantagineum seed oil and sunflower unsaponifiables developed by RAHN AG — which provides documented anti-inflammatory and anti-pruritic (itch-relieving) activity. Paired with Biosaccharide Gum-2 (Rhamnosoft®, a rhamnose-derived polysaccharide) and Cardiospermum halicacabum (balloon vine) extract, the formula targets inflammatory triggers, reduces the appearance of redness, and reinforces skin’s resistance to environmental stress. Aloe barbadensis leaf juice, squalane, and a multi-oil emollient blend (macadamia, avocado, grape seed, meadowfoam, jojoba) complete the barrier-support matrix. The cream is dermatologically tested and substantiated, and is positioned for use on hypersensitive skin including skin that flushes easily. Important note: this cream supports sensitive and redness-prone skin; it is not a medical treatment and makes no claim to diagnose, treat, or cure any skin condition.

Yes to both. The Sensiderm Stress Protect Cream contains no added fragrance (Parfum), no fragrance components, and no alcohol (ethanol / alcohol denat.). INCIDecoder classifies it as both alcohol-free and fragrance & essential oil-free. Dr. Schrammek specifically formulated it without colouring agents, perfumes, parabens, mineral oil, PEG derivatives, and lanolin — the ingredients most commonly associated with reactions on hypersensitive skin. The brand’s US site also confirms it is suitable for vegans, and the formula contains no animal-derived ingredients. This combination makes it one of the cleaner options available for those with multiple sensitizers or confirmed fragrance allergies.

Defensil® is a patented botanical active developed by RAHN AG, a Swiss specialty ingredients company. Its INCI composition is Octyldodecanol, Echium Plantagineum Seed Oil, and Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables. The active core is Echium plantagineum seed oil, which is rich in stearidonic acid and gamma-linolenic acid (GLA) — omega-3 and omega-6 fatty acids with established roles in modulating skin’s inflammatory response. Helianthus annuus unsaponifiables provide complementary skin-identical lipid components. Together, Defensil® is documented to act as an anti-inflammatory, to visibly reduce redness, and to relieve itching (anti-pruritic). Dr. Schrammek uses it as the lead active in the Sensiderm Stress Protect Cream because it addresses the root inflammatory trigger of reactive-skin symptoms rather than masking them.

Yes. Dr. Schrammek’s brand-direct product page categorizes the Sensiderm Stress Protect Cream under both Day Care and Night Care, and the application instructions state “apply morning and evening to face and neck.” The rich, emollient texture draws from macadamia, jojoba, avocado, meadowfoam, and grape seed oils supported by squalane, making it substantive enough to provide overnight barrier recovery without separate day and night products. It contains no SPF, so for daytime use in active sun exposure a separate broad-spectrum sunscreen is recommended over the top. The cream’s fragrance-free, alcohol-free formulation makes it suitable for twice-daily use even on skin that is currently reactive or compromised.

Rhamnosoft® is the trade name for Biosaccharide Gum-2, a polysaccharide produced by bacterial fermentation whose sugar sequence is rich in rhamnose, galactose, and glucuronic acid. According to its manufacturer (Solabia Group), it acts as a protecting agent against environmental aggressors that accelerate skin aging and is described as a booster of skin comfort that stimulates the release of comfort-signaling molecules. In the context of sensitive skin, its rhamnose-rich structure is associated with anti-inflammatory and redness-reducing activity. In the Sensiderm Stress Protect Cream, Rhamnosoft® works alongside Defensil® and Cardiospermum halicacabum extract to provide a multi-pathway calming effect on reactive or environmentally stressed skin.

The Sensiderm Stress Protect Cream is listed at $128.00 on drschrammekusa.com (the brand’s official US store, May 2026) plus applicable taxes. organicskincare.com offers the same 50 ml jar at $95.99 — approximately 25% below the brand’s own direct price — with no add-on tax at checkout for most US states. The formulation is identical: same 50 ml size, same German manufacture, same INCI. The difference reflects organicskincare.com’s position as an authorized multi-brand professional skincare retailer rather than a single-brand store.